| Bionanotechnology in Personalized Medicine: Current Challenges and Future Perspectives |
| Paper ID : 1290-IGA |
| Authors |
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Mehrnoush Ebadi * Department of engineering, bioengineering campus, University of Genova, Italy |
| Abstract |
| Background and Aim: In customized medicine, bionanotechnology—the fusion of nanotechnology and biology—has become a game-changing instrument. It makes molecular precision diagnostics, early illness diagnosis, and tailored medicine administration possible. Notwithstanding these encouraging uses, a number of obstacles stand in the way of implementing bionanotechnological advancements in clinical settings, such as patient-specific variability, scalability, regulatory barriers, and biocompatibility. The purpose of this review is to examine current developments in bionanotechnology in personalized medicine, pinpoint major obstacles, and suggest future paths for clinical integration. Methods: A thorough search of the literature was done with Web of Science, PubMed, and Scopus. "Bionanotechnology," "individualized medicine," "nanocarriers," "targeted drug delivery," and "nanosensors" were among the keywords. Articles written in English and released between 2020 and 2025 were included. Studies that exploited bionanotechnological technologies for personalized monitoring, treatment, and diagnostics were the main emphasis of the selection. We also looked at AI-assisted techniques for designing nanomaterials and predicting patient-specific responses. Results: Numerous applications were found in the review, such as drug delivery systems based on nanoparticles, biomarker detection using nanobiosensors, and diagnostics enabled by nanotechnology customized for each patient's unique profile. The application of AI and machine learning algorithms to forecast treatment results and enhance nanomaterial qualities has grown. Widespread clinical acceptance is nevertheless still constrained by problems like toxicity, customized dosage, and regulatory approval. Conclusion: Because bionanotechnology allows for precise, patient-specific therapies, it has the potential to completely transform personalized medicine. Transforming bionanotechnological advancements into useful healthcare solutions requires addressing present issues through multidisciplinary research, AI integration, and strong clinical validation. |
| Keywords |
| Bionanotechnology, Personalized Medicine, Targeted Drug Delivery, Nanodiagnostics, Precision Therapeutics |
| Status: Accepted |
