| Struma Ovarii: A Rare Cause of Hyperthyroidism and Infertility – Case Report and Literature Review |
| Paper ID : 1252-IGA |
| Authors |
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Besjona Kodra *1, Emirvina Kolici2 1Faculy of Medicine
UHO Mbreteresha Geraldine 2FSHMT |
| Abstract |
| Background and Aim: Struma ovarii is a rare form of ovarian teratoma, made up mostly of thyroid tissue, and accounts for less than 1% of all ovarian tumors. While usually asymptomatic, in a small number of cases the thyroid tissue is hormonally active, leading to hyperthyroidism. Diagnosis before surgery can be difficult due to vague symptoms and nonspecific imaging features. This work aims to provide a concise review of the literature on struma ovarii and share our experience with an unusual case presenting with both infertility and hyperthyroidism. Materials and Methods: We reviewed the current literature on struma ovarii, with a focus on clinical presentation, diagnostic challenges, imaging features, and treatment approaches. Additionally, we present a case managed at our hospital and compare it with findings from the literature. Results: A 41-year-old woman undergoing infertility evaluation was found to have biochemical hyperthyroidism. Transvaginal ultrasound identified a 63 mm ovarian cyst with dermoid-like characteristics. Tumor markers were within normal range (CA-125: 6.35 U/mL; HE4: 40.5 pmol/L). Laparoscopic surgery was performed, and histopathological analysis confirmed the diagnosis of struma ovarii. No further treatment was needed postoperatively, and thyroid function normalized by the 6-week follow-up. Conclusions: Functional struma ovarii is rare and often diagnosed only after histopathology. However, surgical removal is typically curative, resolving both pelvic and thyroid-related symptoms. Clinicians should keep struma ovarii in mind when encountering patients with complex ovarian masses, particularly if associated with unexplained hyperthyroidism or infertility. |
| Keywords |
| Struma ovarii, ovarian teratoma, hyperthyroidism, infertility, thyroid tissue, case report, gynecologic surgery |
| Status: Accepted |
