| STAb CAR-T Cells: Pioneering Precision in Cancer Immunotherapy For ICBMS25 Conference |
| Paper ID : 1243-IGA |
| Authors |
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Manal Mohamed Elsayed Ahmed * Medical Research and Clinical Studies Institute, National Research Centre, Egypt |
| Abstract |
| STAb CAR-T Cells: Pioneering Precision in Cancer Immunotherapy Manal M E Ahmed Pharmacology Department, Medical Research and clinical studies institute, National Research Centre, Giza, Egypt. Email address: thinktankteam2014@gmail.com Phone No: +20 1093627027 Abstract Chimeric Antigen Receptor (CAR) T cell therapy has revolutionized cancer treatment, particularly for hematologic malignancies. However, challenges such as limited efficacy in solid tumors and antigen escape have prompted the development of novel approaches. One such innovation is the STAb (Synthetic T-cell Activating Bifunctional) CAR-T cells, which aim to enhance the therapeutic potential of CAR-T cells. The development of STAb CAR T cells represents a significant advancement in the field of cancer immunotherapy. By overcoming some of the key obstacles faced by traditional CAR-T cells, STAb CAR-T cells hold promise for more effective and versatile cancer treatments. This review will investigate the functioning, benefits, clinical trials, obstacles, and future prospects of STAb CAR-T cells, underscoring their transformative potential in cancer treatment. |
| Keywords |
| CAR-T cell therapy, Hematological malignancies, Solid tumors, Immunotherapy, Precision medicine |
| Status: Accepted |
