| Advanced Therapeutic Approaches for Skin Complications Associated with Polycystic Ovary Syndrome (PCOS): A Decade in Review (2015–2025) |
| Paper ID : 1228-IGA |
| Authors |
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Shiva Ghafarinejad * Department of Biology, University of Basic Sciences, Islamic Azad University, Rudehen Branch, Tehran, Iran |
| Abstract |
| Background and Aim: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age, often accompanied by a range of skin complications including acne, hirsutism, seborrhea, and acanthosis nigricans. These dermatological manifestations significantly impact patients' quality of life and self-esteem. This review aims to summarize and evaluate the most recent and advanced treatment approaches targeting skin-related complications in PCOS, highlighting both pharmacological and non-pharmacological interventions. Materials and Methods: A comprehensive literature search was conducted using the keywords: “PCOS,” “skin complications,” “acne,” “hirsutism,” “treatment,” “laser therapy,” “hormonal therapy,” and “advanced dermatological interventions.” Databases searched included PubMed, ScienceDirect, Scopus, and Google Scholar. Only peer-reviewed English-language journals published between 2015 and 2025 were included. Exclusion criteria were non-English articles, studies prior to 2015, and research not directly addressing skin manifestations of PCOS. Results: Recent advances highlight the efficacy of combination therapies involving hormonal agents (e.g., combined oral contraceptives, anti-androgens), topical treatments (e.g., retinoids, azelaic acid), and cosmetic procedures such as laser hair removal and light-based therapies. Emerging trends include the use of nutraceuticals, low-level laser therapy, and personalized treatment plans based on hormonal profiling and skin type. Conclusion: Advanced treatment strategies for PCOS-related skin complications are increasingly patient-centered and multidisciplinary. An integrated approach combining medical, dermatological, and lifestyle interventions shows promise in improving clinical outcomes and enhancing patient satisfaction. |
| Keywords |
| PCOS, Skin complications, Acne, Hirsutism, Hormonal therapy, Laser treatment, Women’s health |
| Status: Accepted |
