| What We Know about PSORIASIS So Far? |
| Paper ID : 1222-IGA |
| Authors |
|
Gheorghe Giurgiu * Deniplant-Aide Sante Medical Center, Biomedicine, Bucharest, Romania |
| Abstract |
| Background and Aim: Restoration of the dysbiotic gut microbiome has emerged as a promising aid and a better therapeutic approach. New evidences suggest that the microbiome may play a pathogenic role in psoriatic disease. The aim of the present project is to investigate whether a dietary intervention could ameliorate the clinical manifestations and modulate the gut microbiota of individuals with psoriasis. Materials and Methods: Relevant literature from the past decade was reviewed using electronic databases to summarize current evidence on the impact of diet and gut microbiota modulation in the management of psoriasis. Results: Among environmental factors, diet plays a central role therefore incorrect nutritional habits and excessive body weight can increase clinical symptoms or even trigger the disease. Such diet-based and nutraceutical approaches to targeting the microbiome may produce a milder side effect profile than current systemic medications. Thus, interventions aimed at the microbiome may be a valuable adjunct for preventing or managing psoriatic disease and its comorbidities. Conclusion: Nutrition plays an important role in the development of psoriasis and its comorbidities. Ultimately, a better understanding of the psoriatic microbiome can lead to the development of new therapeutic modalities that target the shifting microbiota. Thus, interventions aimed at the microbiome may be a valuable adjunct for preventing or managing psoriatic disease and its comorbidities. |
| Keywords |
| Psoriasis, Microbiome, Microbiota, Deniplant nutraceuticals |
| Status: Accepted |
