| Genomic Profiling of Tumors: A Gateway to Personalized Cancer Treatments |
| Paper ID : 1190-IGA |
| Authors |
|
Sahar Saki *1, Parand TorabiParizi2 1Department of Biology, Faculty of converging Sciences and Technologies, Science and Research Branch, Islamic Azad University, Tehran, Iran 2Department of Biology, Faculty of Basic Sciences, Damghan Branch, Islamic Azad University, Damghan, Iran |
| Abstract |
| Background and Aim: Cancer is a complex disease and Traditional treatments, such as chemotherapy, are not always effective and may lead to various side effects. Therefore, personalized treatments, which are tailored based on the genetic profile of each patient's tumor, have become increasingly important. Tumor genetic profiling aids in identifying genetic and molecular alterations, which can help in selecting more targeted and effective therapies. The aim of this review article is to explore the role of tumor genetic profiling in personalized cancer treatment. Materials and Methods: In this review, a comprehensive literature search was conducted using databases such as PubMed, Scopus, and Google Scholar to gather relevant studies on tumor genetic profiling and personalized cancer treatments. Predefined inclusion and exclusion criteria were applied to select peer-reviewed articles focusing on genetic profiling techniques, personalized therapies, and their clinical applications. Results: The reviewed studies indicate that the genetic profile of tumors which are crucial for personalized cancer treatments. Advanced techniques, such as next-generation sequencing (NGS), have made it possible to identify specific mutations and offer effective targeted therapies for different types of cancers. Conclusion: Genetic profiling of tumors plays a pivotal role in advancing personalized cancer treatments by identifying specific genetic alterations that drive tumor growth and response to therapies. The integration of advanced genomic technologies, such as next-generation sequencing, has significantly improved the accuracy of tumor profiling, leading to more targeted and effective treatments. |
| Keywords |
| Genomic Profiling, Personalized Cancer Treatment, Tumor Genomics, Targeted Therapy |
| Status: Accepted |
