| Assessment of the impact of heating a feeding oil mixture on laboratory rats' lipid profiles and liver functions |
| Paper ID : 1172-IGA |
| Authors |
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Medhat Mostafa Abozid * Biochemistry department, Faculty of Agriculture, Menoufia University, Egypt |
| Abstract |
| Since Egyptians frequently cook with a mixture of heated oils, heated oils are regarded as a common tradition in daily life in the Arab Republic of Egypt. Therefore, it is necessary to investigate the effects of this on lipid indicators and liver functions in laboratory animals in order to determine the extent of its danger or safety to humans. Thus, 36 albino rats were used in a laboratory experiment, and they were split into six groups: the control group was given a regular diet, the fresh soybean oil group, the fresh sunflower oil group, the fresh olive oil group, the fresh mix oil group, and the mix heated oil group. Biological experiments revealed that heated oils significantly elevated malondialdehyde (MDA) levels, indicating increased oxidative stress. They also worsened lipid profiles by raising triglycerides, LDL, and VLDL while lowering HDL cholesterol. In contrast, fresh oils, especially olive oil, improved lipid profiles by increasing HDL and reducing other lipid fractions. Heated oils negatively impacted liver function by elevating serum enzyme activities (GPT, GOT, and GGT) and bilirubin levels, reflecting oxidative stress and liver damage. Conversely, fresh oils reduced enzyme activities and bilirubin levels, demonstrating protective effects on liver function. Protein metabolism markers (total protein, albumin, and globulin) also decreased with heated oils but improved significantly with fresh oils. In conclusion, heated oils exacerbated oxidative stress, impaired lipid metabolism, and damaged liver function, while fresh oils, particularly olive oil, exhibited antioxidant properties, improved lipid and liver function, and supported overall health. These findings highlight the health risks of consuming repeatedly heated oils and the benefits of using fresh oils in diets. |
| Keywords |
| Heated oils - Liver functions - Lipid profile - Fresh oils |
| Status: Accepted |
