| Nanovesicles from Fruit Extracts for Breast Cancer Therapy |
| Paper ID : 1155-IGA |
| Authors |
|
Afrooz Sepahvand * Department of Cellular and Molecular Biology,
Faculty of Advanced Science and Technology,
Tehran Medical Sciences, Islamic Azad
University, Tehran, Iran |
| Abstract |
| Nanobiotechnology has revolutionized cancer treatment, offering new strategies for targeted drug delivery. Nanovesicles, in particular those synthesized using biological sources such as fruit extracts, can be applied for cancer treatment, This tudy aims to review the application of nanovesicles synthesized from fruit extracts in breast cancer treatment. Methods: The published papers were reviewed using well-known sources such as Google Scholar, PubMed, Clarivate, ScienceDirect, and Scopus. The key terms including nanovesicles," "fruit extract," "cancer," "breast cancer," and "treatment" were used to find the best related papers. Peer-reviewed articles and clinical studies published in the last decade were reviewed and analyzed Results: Recently research has focused on the potential of fruit extract-derived nanovesicles (FDNVs) application in breast cancer treatment. Early studies revealed the significant antioxidant properties of FDNVs. As research progressed, scientists found that FDNVs can be applied in targeted drug delivery systems; for instance, ginger-derived anoparticles could enhance the delivery capabilities in cancer models. Isolating and characterizing FDNVs from fruits like blueberries and citrus, has been reported recently to increase the ability of nanovesicles to induce the cancer signaling pathways in vitroin cancer cells including breast cancer cells. Conclusion: Although there are significant challenges in application of FDNVs for breast treatment, the research underscores the potential of FDNVs as therapeutic agents cancer in cancer treatment as well as using FDNVs as vehicles for chemotherapeutic drugs. urther in vitro and in vivo research are required to reveal the exact role played by FDNVs in breast cancer therapy. |
| Keywords |
| Fruit extract-derived nanovesicles, Drug delivery systems, Breast cancer therapy, Targeted treatment, Nano-based therapeutics |
| Status: Accepted |
