| Fruit Extract-Derived Nanovesicles for Breast Cancer Treatment |
| Paper ID : 1147-IGA |
| Authors |
|
Atefeh Hasanli * Department of Nanobiotechnology, Faculty of Biological Science, Tarbiat Modares University, Tehran, Iran |
| Abstract |
| Background and Aim: Nanobiotechnology has revolutionized cancer treatment, offering new strategies for targeted drug delivery. Nanovesicles, in particular those synthesized using biological sources such as fruit extracts, can be applied for cancer treatment. This study aims to review the application of nanovesicles synthesized from fruit extracts in breast cancer treatment. Methods: The published papers were reviewed using well-known sources such as Google Scholar, PubMed, Clarivate, ScienceDirect, and Scopus. The key terms including “nanovesicles,” “fruit extract,” “cancer,” “breast cancer,” and “treatment” were used to find the best related papers. Peer-reviewed articles and clinical studies published in the last decade were reviewed and analyzed. Results: Recently research has focused on the potential of fruit extract-derived nanovesicles (FDNVs) application in breast cancer treatment. Early studies revealed the significant antioxidant properties of FDNVs. As research progressed, scientists found that FDNVs can be applied in targeted drug delivery systems; for instance, ginger-derived nanoparticles could enhance the delivery capabilities in cancer models. Isolating and characterizing FDNVs from fruits like blueberries and citrus, has been reported recently to increase the ability of nanovesicles to induce the cancer signaling pathways in vitro in cancer cells including breast cancer cells. Conclusion: Although there are significant challenges in application of FDNVs for breast cancer treatment, the research underscores the potential of FDNVs as therapeutic agents in cancer treatment as well as using FDNVs as vehicles for chemotherapeutic drugs. Further in vitro and in vivo research are required to reveal the exact role played by FDNVs in breast cancer therapy. |
| Keywords |
| Fruit extract-derived nanovesicles, Drug delivery, Breast cancer, Treatment |
| Status: Accepted |
