| Ganoderma Extracts, Pharmacological Properties and Biomedical Applications |
| Paper ID : 1143-IGA |
| Authors |
|
Zahedeh Koulivand * Department of Biology, Islamic Azad University, Hamadan Branch, Hamadan, Iran |
| Abstract |
| Background and Aim: Ganoderma, particularly Ganoderma lucidum, commonly known as Reishi or Lingzhi, has been used in East Asian traditional medicine for many years to treat a variety of diseases and wounds. Studies have shown that Ganoderma extract has antioxidant, anti-inflammatory, and anticancer effects. The aim of this study is to review the pharmacological properties of Ganoderma extracts and their biomedical applications. Method: We explored Google scholar, PubMed, Scopus, and Web of Science to extract the data using keywords such as “Ganoderma”, “pharmacological properties”, “biomedicine”, and “biomedical application”. Experimental studies concerned with the pharmacological properties of Ganoderma extracts and their biomedical applications were explored. Results: Ganoderma extracts are rich in bioactive compounds, including triterpenes, polysaccharides, and phenolic compounds, which contribute to their pharmacological effects including antioxidant activity, antimicrobial effects, antitumor activity, anti-inflammatory properties, and immunomodulatory effects. The pharmacological properties of Ganoderma extracts make them suitable for biomedical applications such as cancer therapy, dietary supplements aimed at enhancing overall health, cosmetic formulations, particularly in skin care products targeting aging and inflammation, and pharmaceutical formulations for the treatment of various diseases, including metabolic disorders, cardiovascular diseases, and infections. Conclusion: Ganoderma extracts, particularly from G. lucidum, have been reported to have significant pharmacological properties. The antioxidant property of Ganoderma extracts make them valuable in biomedical applications ranging from cancer therapy to cosmetic formulations. Further research particularly focusing on the mechanism of Ganderma extracts action on target cells can reveal their biomedical effects in target tissues. |
| Keywords |
| Ganoderma extracts, Pharmacological properties, Biomedical applications |
| Status: Accepted |
