| Synergistic Effects of Traditional Plant Drugs and Synthetic Pharmaceuticals: A New Frontier in Pharmacology |
| Paper ID : 1124-IGA |
| Authors |
|
Yasaman Aliyan * Department of Biology, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran |
| Abstract |
| Background and Aim: Traditional plant drugs have been shown to have significant effects on human diseases. Additionally, advanced synthetic pharmaceuticals have been applied in modern medicine in recent decades. The synergistic effects of combining these two approaches have been studied by scientist demonstrating a body of evidences supporting the synergism. This review aims to investigate the potential synergistic interactions between traditional plant-based medicines and synthetic pharmaceuticals. Methods: A thorough literature search was conducted using key terms including “synergistic effects,” “traditional plant drugs,” “synthetic pharmaceuticals,” “combination therapy,” and “pharmacology.” Data was collected from multiple databases, including Google Scholar, PubMed, Clarivate, ScienceDirect, and Scopus. Relevant peer-reviewed articles published in the last 20 years were analyzed to assess the outcomes of combining traditional plant drugs with synthetic pharmaceuticals. Results: Analyzed data show the enhanced therapeutic effects of traditional plant drugs when used in combination with synthetic pharmaceuticals. Examples include improved efficacy in cancer treatments, anti-inflammatory responses, and cardiovascular therapies. The findings demonstrate that the adverse effects have been significantly decreased. Additionally, the review identifies key pharmacokinetic and pharmacodynamic interactions that underpin these synergistic effects. Conclusion: The synergistic combination of traditional plant drugs and synthetic pharmaceuticals offers a promising approach to developing more effective and safer therapeutic strategies. Although there are contradictory opinions, using this approach in pharmaceutical companies could pave the way for innovative treatments, enhancing the efficacy of both traditional and modern medicine. Further research is required to fully understand the mechanisms behind these interactions and to optimize their clinical applications. |
| Keywords |
| Synergistic effects, Traditional plant drugs, Synthetic pharmaceuticals, Pharmacology |
| Status: Accepted |
